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Studies

Observational Recruiting

NCT05538806 on ClinicalTrials.gov

TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study

Official title: TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study - TIGER Meso Study

  • Sponsor: Novocure (United States)
  • Enrollment: 198 (Estimated)
  • Study start: 2023-08-01 (Actual)
  • Primary completion: 2027-12-01 (Estimated)
  • Study completion: 2028-06-01 (Estimated)
  • Allocation: N/a
  • InterventionModel: N/a
  • Masking: None
  • PrimaryPurpose: Other

Brief Summary

The purpose of this post-authorisation medical device study is to obtain real life data on the use of Tumor Treating Fields (TTFields) in patients with pleural mesothelioma in routine clinical care. Patients with pleural mesothelioma and clinical indication for TTFields treatment will be enrolled in the study after signing Informed consent to use their data and process it centrally for research purposes. The clinical indication for TTFields is one of the inclusion criteria and is defined prior to inclusion by the treating physician.

Conditions

  • Pleural Mesothelioma

Intervention / Treatment

  • Device: TTFields

Primary Outcome Measures

  • Time from diagnosis of pleural mesothelioma to death of any cause as median overall survival time. (54 Months)

Countries

Germany, Italy, Netherlands

Locations and Investigators

  • Lungenklinik Gauting, Gauting, Germany (Recruiting)
    • Rudolf A Hatz
  • University Hospital Regensburg, Regensburg, Germany (Recruiting)
    • Michael Ried
  • Asklepios Klinikum Harburg, Hamburg-Harburg, Germany (Recruiting)
    • Claas Wesseler
  • University Medicine Göttingen, Göttingen, Germany (Recruiting)
    • Rami El-Shafie
  • University Hospital Carl Gustav Carus Dresden, Dresden, Germany (Recruiting)
    • Till Ploenes
  • Charité Universitätsmedizin Berlin, Berlin, Germany (Recruiting)
    • Nikolaj Frost
  • Lungenklinik Heckeshorn, Berlin, Germany (Recruiting)
    • Daniel Misch
  • Klinikum Bremen-Ost, Bremen, Germany (Recruiting)
    • André Bethge
  • Kliniken der Stadt Koeln, Cologne, Germany (Recruiting)
    • Carolin Gross-Ophoff-Müller
  • Florence-Nightingale-Hospital, Düsseldorf, Germany (Recruiting)
    • Aris Koryllos
  • Klinikum Essen-Mitte, Essen, Germany (Recruiting)
    • Konstantinos Ferrentinos
  • University Hospital Essen, Essen, Germany (Recruiting)
    • Martin Metzenmacher
  • Niels-Stensen Hospital, Georgsmarienhütte, Germany (Recruiting)
  • Krankenhaus Martha-Maria Halle-Doelau, Halle, Germany (Recruiting)
    • Wolfgang Schuette
  • Medizinische Hochschule Hannover, Hannover, Germany (Recruiting)
    • Heiko Golpon
  • Lungenklinik Hemer, Hemer, Germany (Recruiting)
    • Karsten Schulmann
  • Evangelisches Krankenhaus Herne, Herne, Germany (Recruiting)
    • Daniel Christoph
  • Krankenhaus Bethanien Moers, Moers, Germany (Recruiting)
    • Kato Kambartel
  • GEHO Muenster, Muenster, Germany (Recruiting)
    • Rüdiger Liersch
  • Fachkliniken Wangen, Wangen, Germany (Recruiting)
    • Philipp Meyn
  • Azienda Ospedaliero-Universitaria di Alessandria "SS. Antonio e Biagio e C. Arrigo", Alessandria, Italy (Recruiting)
    • Federica Grosso
  • Humanitas Gavazzeni, Bergamo, Italy (Recruiting)
  • Erasmus MC Cancer Centre, Rotterdam, Netherlands (Recruiting)
    • Joachim Aerts