Observational Recruiting
NCT05752812 on ClinicalTrials.gov
The HELPP Score: A Pretreatment Score to Predict Survival in Pancreatic Cancer
Official title: The HELPP Score: A Pretreatment Prognostic Score to Predict Survival and Patterns of Recurrence in Localized Non-Metastatic Pancreatic Cancer - a Multicenter Prospective Validation Study
- Sponsor: Medical University of Vienna
- Enrollment: 1500 (Estimated)
- Study start: 2023-03-01 (Actual)
- Primary completion: 2026-05-01 (Estimated)
- Study completion: 2026-11-01 (Estimated)
- Allocation: N/a
- InterventionModel: N/a
- Masking: None
- PrimaryPurpose: Other
Brief Summary
The goal of this observational study is to validate a pretreatment prognostic score (Heidelberg Prognostic Pancreatic Cancer Score - HELPP) in patients with pancreatic ductal adenocarcinoma.
The main questions it aims to answer are:
* Is the HELPP score able to predict median overall survival in a prospective multi-institutional cohort of patients with pretherapeutic localized non-metastatic pancreatic cancer?
* Is the HELPP score able to predict median recurrence-free survival and patterns of recurrence after resection of pancreatic cancer?
Conditions
- Pancreatic Adenocarcinoma
Primary Outcome Measures
-
Median overall survival
(Date of diagnosis to date of death; assessed up to 60 months)
Median overall survival from the time of diagnosis with pancreatic ductal adenocarcinoma to time of death due to any cause.
Countries
Austria
Locations and Investigators
-
Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria (Recruiting)
- Carl Leonhardt
- Carl Leonhardt, MD, MBA
- Oliver Strobel, MD, MBA (Principal Investigator)
Study Officials
- Oliver Strobel, MD MBA (Study Director) — Medical University Vienna