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Studies

Interventional Active not recruiting

NCT05896189 on ClinicalTrials.gov

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Official title: Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors: A Multi-Center Randomized Double-Blinded Controlled Trial

  • Sponsor: NRG Oncology
  • Collaborators: National Cancer Institute (NCI)
  • Enrollment: 386 (Estimated)
  • Study start: 2024-02-29 (Actual)
  • Primary completion: 2027-02-28 (Estimated)
  • Study completion: 2027-11-30 (Estimated)
  • Allocation: Randomized
  • InterventionModel: Parallel
  • Masking: Double (Participant, Outcomes Assessor)
  • PrimaryPurpose: Prevention

Brief Summary

This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors.

Conditions

  • Breast Cancer
  • Cognitive Impairments

Intervention / Treatment

  • Behavioral: Arm 1: Computerized Cognitive Training-Global Stimulation Games
  • Behavioral: Arm 2: Computerized Cognitive Training-Neuroplasticity Games

Primary Outcome Measures

  • Self-reported perceived cognitive impairment measured-post intervention (12 weeks from randomization)
    FACT-Cog PCI scale score (Functional Assessment of Cancer Therapy-Cognitive Function-perceived cognitive impairment)

Countries

Puerto Rico, United States

Locations and Investigators

  • Anchorage Associates in Radiation Medicine, Anchorage, United States
  • Anchorage Radiation Therapy Center, Anchorage, United States
  • Alaska Breast Care and Surgery LLC, Anchorage, United States
  • Alaska Oncology and Hematology LLC, Anchorage, United States
  • Alaska Women's Cancer Care, Anchorage, United States
  • Katmai Oncology Group, Anchorage, United States
  • Providence Alaska Medical Center, Anchorage, United States
  • Fairbanks Memorial Hospital, Fairbanks, United States
  • Arizona Center for Cancer Care - Gilbert, Gilbert, United States
  • CTCA at Western Regional Medical Center, Goodyear, United States
  • Arizona Center for Cancer Care-Peoria, Peoria, United States
  • Cancer Center at Saint Joseph's, Phoenix, United States
  • Arizona Center for Cancer Care - Biltmore, Phoenix, United States
  • Arizona Center for Cancer Care - Phoenix, Phoenix, United States
  • Mayo Clinic Hospital in Arizona, Phoenix, United States
  • Arizona Center for Cancer Care - Osborn, Scottsdale, United States
  • Arizona Center for Cancer Care - Scottsdale, Scottsdale, United States
  • Arizona Center for Cancer Care-Surprise, Surprise, United States
  • Arizona Center for Cancer Care, Tempe, United States
  • Mercy Hospital Fort Smith, Fort Smith, United States
  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro, United States
  • CARTI Cancer Center, Little Rock, United States
  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, United States
  • AIS Cancer Center at San Joaquin Community Hospital, Bakersfield, United States
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, United States
  • Marshall Cancer Center, Cameron Park, United States
  • Mercy Cancer Center - Carmichael, Carmichael, United States
  • Mercy San Juan Medical Center, Carmichael, United States
  • Enloe Medical Center, Chico, United States
  • Kaiser Permanente Dublin, Dublin, United States
  • Mercy Cancer Center - Elk Grove, Elk Grove, United States
  • Kaiser Permanente-Fremont, Fremont, United States
  • Washington Hospital, Fremont, United States
  • Fresno Cancer Center, Fresno, United States
  • Kaiser Permanente Fresno Orchard Plaza, Fresno, United States
  • Kaiser Permanente-Fresno, Fresno, United States
  • Cedars Sinai Medical Center, Los Angeles, United States
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, United States
  • Contra Costa Regional Medical Center, Martinez, United States
  • Fremont - Rideout Cancer Center, Marysville, United States
  • Mercy Cancer Center, Merced, United States
  • Kaiser Permanente- Modesto MOB II, Modesto, United States
  • Kaiser Permanente-Modesto, Modesto, United States
  • Providence Queen of The Valley, Napa, United States
  • Kaiser Permanente-Oakland, Oakland, United States
  • Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, United States
  • Kaiser Permanente- Marshall Medical Offices, Redwood City, United States
  • Kaiser Permanente-Richmond, Richmond, United States
  • Mercy Cancer Center - Rocklin, Rocklin, United States
  • Rohnert Park Cancer Center, Rohnert Park, United States

And 630 other sites.