Observational Recruiting
NCT06516406 on ClinicalTrials.gov
Ruxolitinib in Primary Myelofibrosis and Secondary to Essential Thrombocythemia or Polycythemia Vera
- Sponsor: Policlinico S.Orsola-Malpighi
- Enrollment: 1055 (Estimated)
- Study start: 2022-05-06 (Actual)
- Primary completion: 2032-05-31 (Estimated)
- Study completion: 2032-05-31 (Estimated)
- Allocation: N/a
- InterventionModel: N/a
- Masking: None
- PrimaryPurpose: Other
Brief Summary
The study is observational multicenter retrospective and prospective cohort study of patients with primary or secondary myelofibrosis who have initiated therapy with ruxolitinib, prescribed as part of the normal course of care and completely independent of study participation. The primary purpose is to determine the impact of clinical and laboratory characteristics of myelofibrosis on the prognosis of patients treated with ruxolitinib, understood as long-term survival.
Conditions
- Myelofibrosis
- Primary Myelofibrosis
- Secondary Myelofibrosis
Primary Outcome Measures
-
Long Term Survival
(10 years)
To determine the impact of clinical and laboratory characteristics of myelofibrosis on the prognosis of patients treated with ruxolitinib, in terms of long-term survival.
Countries
Italy
Locations and Investigators
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Azienda Ospedaliera Annunziata, Cosenza, Italy (Recruiting)
- Francesco Mendicino, MD
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Grande Ospedale Metropolitano "Bianchi Melacrino Morelli", Reggio Calabria, Italy (Recruiting)
- Bruno Martino, MD
-
Università degli Studi di Napoli Federico II U.O.C. di Ematologia e Trapianti di midollo, Napoli, Italy (Recruiting)
- Novella Pugliese, MD
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IRCCS Policlinico Sant'Orsola, Bologna, Italy (Recruiting)
- Francesca Palandri, MD, PhD
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Università degli studi di Ferrara - Nuovo Polo Ospedaliero di Cona - A.O.U. Arcispedale S. Anna, Ferrara, Italy (Recruiting)
- Francesco Cavazzini, MD
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Azienda Ospedaliero-Universitaria di Parma, Parma, Italy (Recruiting)
- Monica Crugnola, MD
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AUSL di Piacenza - Palazzine Medicine Specialistiche, Piacenza, Italy (Recruiting)
- Costanza Bosi, MD
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Dipartimento Oncoematologico - AUSL della Romagna, Ravenna, Italy (Recruiting)
- Francesco Lanza, MD
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Ospedale Infermi di Rimini, Rimini, Italy (Recruiting)
- Simona Tomassetti, MD
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A.O.U. Integrata di Udine, Udine, Italy (Recruiting)
- Mario Tiribelli, MD
- A.O.U. Policlinico Umberto I - Università degli Studi di Roma "La Sapienza", Roma, Italy (Recruiting)
- Ospedale S. Eugenio, Roma, Italy (Recruiting)
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Ospedale Belcolle, Viterbo, Italy (Recruiting)
- Roberto Latagliata, MD
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IRCCS Azienda Ospedaliera Universitaria "San Martino" - IST, Genova, Italy (Recruiting)
- Roberto Lemoli, MD
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy (Recruiting)
- Alessandra Iurlo, MD
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Ospedale San Gerardo, Monza, Italy (Recruiting)
- Elena Elli, MD
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A.O. Ospedali Riuniti Marche Nord - Presidio Ospedaliero San Salvatore, Pesaro, Italy (Recruiting)
- Alessandro Isidori, MD
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Ospedale San Luigi Gonzaga - Regione Gonzole, Torino, Italy (Recruiting)
- Daniela Cilloni, MD
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Department of Oncology, University of Torino, Torino, Italy (Recruiting)
- Eloise Beggiato, MD
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Città della Salute e della Scienza, Torino, Italy (Recruiting)
- Giulia Benevolo, MD
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A. O. Ordine Mauriziano di Torino, Torino, Italy (Recruiting)
- Daniela Cilloni, MD
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Ospedale "A. Businco" - Dipartimento Scienze Mediche e Sanità Pubblica Università degli Studi di Cagliari, Cagliari, Italy (Recruiting)
- Giovanni Caocci, MD
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A.O.U. "Policlinico-V. Emanuele"- P.O. Ferrarotto, Catania, Italy (Recruiting)
- Giuseppe Palumbo, MD
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Policlinico S.Maria alle Scotte, Siena, Italy (Recruiting)
- Monica Bocchia, MD
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AOU di Padova, Padova, Italy (Recruiting)
- Gianni Binotto, MD
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A.O.U. Integrata Verona, Verona, Italy (Recruiting)
- Massimiliano Bonifacio, MD