System Maintenance Notice

Please note that maintenance work is scheduled between 4 AM and 5 AM - CET. During this time, you may experience reduced performance. Thanks for your patience.

Studies

Interventional Recruiting

NCT06517589 on ClinicalTrials.gov

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

Official title: Process-based Therapy vs. Routine-CBT for Difficult-to-treat Anxiety Disorders and Depression

  • Sponsor: Goethe University Frankfurt
  • Collaborators: Philipps University Marburg Medical Center
  • Enrollment: 80 (Estimated)
  • Study start: 2024-01-29 (Actual)
  • Primary completion: 2024-12-31 (Estimated)
  • Study completion: 2025-07-30 (Estimated)
  • Allocation: Randomized
  • InterventionModel: Parallel
  • Masking: Single (Outcomes Assessor)
  • PrimaryPurpose: Treatment

Brief Summary

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

Conditions

  • Depression
  • Anxiety Disorder

Intervention / Treatment

  • Other: Process-based Cognitive Behavioral Therapy (PBT)
  • Other: Cognitive Behavioral Therapy (CBT)

Primary Outcome Measures

  • Depression Anxiety Stress Scale (DASS-21) (Assessed at inclusion, at pre-treatment, at post-treatment (week 32) and at 6 month follow-up)
    Emotional distress, minimum value=0, maximum value=63, higher scores mean worse outcome

Countries

Germany

Locations and Investigators

  • JWGUniversity, Frankfurt am Main, Germany (Recruiting)
    • Ulrich Stangier, Prof.
    • Stangier
    • Ulrich Stangier (Principal Investigator)