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Studies

Interventional Recruiting

NCT06789692 on ClinicalTrials.gov

Reduce Tobacco Use in People Living With HIV in Switzerland

Official title: Reduce Tobacco Use in People Living With HIV in Switzerland: A Pragmatic Randomized Trial Within the Swiss HIV Cohort Study

  • Sponsor: University Hospital of Basel
  • Collaborators: Swiss National Science Foundation, Novartis Foundation for Medical-Biological Research
  • Enrollment: 972 (Estimated)
  • Study start: 2025-02-20 (Actual)
  • Primary completion: 2027-12-01 (Estimated)
  • Study completion: 2027-12-01 (Estimated)
  • Allocation: Randomized
  • InterventionModel: Parallel
  • InterventionModelDescription: Randomized Clinical Trial using the Trials within Cohorts (TwiCs) design
  • Masking: None
  • PrimaryPurpose: Prevention

Brief Summary

The purpose of this trial is to test the effectiveness of offering a menu of different tobacco smoking substitutional products (e-cigarettes, nicotine pouches, nicotine patches in addition to usual of care) for smokers in the SHCS (Swiss HIV Cohort Study) in achieving self-reported 7-day tobacco cigarette abstinence at 6 months.

Conditions

  • HIV
  • Smoking

Intervention / Treatment

  • Other: tobacco smoking substitution products

Primary Outcome Measures

  • Tobacco smoking status (yes/no) (at 6 month visit)
    Measured as self-reported abstinence in the last 7 day at 6-month visit

Countries

Switzerland

Locations and Investigators

  • University Hospital Basel, Basel, Switzerland (Completed)
  • Inselspital Bern, Bern, Switzerland (Recruiting)
    • Gilles Wandeler, Prof.
    • Gilles Wandeler, Prof. (Principal Investigator)
  • Cantonal Hospital St. Gallen, Sankt Gallen, Switzerland (Recruiting)
    • Patrick Schmid, Dr.
    • Tamara Dörr, Dr.
    • Patrick Schmid, Dr. (Principal Investigator)
  • University Hospital Lausanne, Lausanne, Switzerland (Recruiting)
    • Matthias Cavassini, Prof.
    • Matthias Cavassini, Prof. (Principal Investigator)
  • University Hospital Zurich, Zurich, Switzerland (Recruiting)
    • Johannes Nemeth, Dr.
    • Johannes Nemeth, Dr. (Principal Investigator)
  • Cantonal Hospital Aarau, Aarau, Switzerland (Recruiting)
    • Christoph Fux, MD
    • Christoph Fux, MD (Principal Investigator)
  • University Hospital Geneva, Geneva, Switzerland (Recruiting)
    • Alexandra Calmy, Prof.
    • Alexandra Calmy, Prof. (Principal Investigator)

Study Officials