Observational Active not recruiting
NCT06895213 on ClinicalTrials.gov
Evaluation of Plasma Renin Concentrations in Cardiac Surgery
- Sponsor: Mayo Clinic (Group)
- Enrollment: 100 (Estimated)
- Study start: 2025-04-14 (Actual)
- Primary completion: 2026-12-01 (Estimated)
- Study completion: 2026-12-01 (Estimated)
- Allocation: N/a
- InterventionModel: N/a
- Masking: None
- PrimaryPurpose: Other
Brief Summary
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.
Conditions
- Cardiac Surgery With Cardiopulmonary Bypass
Primary Outcome Measures
- Plasma renin concentrations (Up to 24 hours after surgery)
Countries
United States
Locations and Investigators
- Mayo Clinic, Rochester, United States
Study Officials
- Patrick M Wieruszewski, Pharm.D. (Principal Investigator) — Mayo Clinic