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Studies

Interventional Recruiting

NCT07557199 on ClinicalTrials.gov

Promoting Interventions for Climate Change to Upscale Resilience in District Astore

Official title: Promoting Interventions for Climate Change to Upscale Resilience (PICCTURE) Trial in District Astore

  • Sponsor: Dr Jai Kumar Das
  • Collaborators: The Hospital for Sick Children, International Development Research Centre, Canada
  • Enrollment: 1350 (Estimated)
  • Study start: 2026-06-01 (Actual)
  • Primary completion: 2027-04-30 (Estimated)
  • Study completion: 2027-05-01 (Estimated)
  • Allocation: Randomized
  • InterventionModel: Parallel
  • InterventionModelDescription: This study is a three-arm, parallel-group cluster randomized controlled trial conducted in District Astore. Clusters are defined as villages or groups of villages to reflect the local geographic and administrative structure and to minimize contamination across study arms. A total of 30 clusters will be randomly selected from all eligible clusters and allocated in a 1:1:1 ratio to: (1) community-based intervention, (2) community-based intervention plus primary healthcare engagement, and (3) control. This design enables estimation of both the independent effect of community-based interventions and the incremental benefit of integrating primary healthcare providers and Lady Health Workers.
  • Masking: None
  • PrimaryPurpose: Prevention

Brief Summary

The PICCTURE trial is a cluster randomized controlled study that will be conducted in District Astore, Pakistan, to evaluate the effectiveness of community-based interventions in improving resilience to climate-related hazards. The study compares community-led adaptation and resilience strategies and community interventions integrated with primary healthcare engagement against a control group. The objective is to determine whether these approaches improve household-level resilience, adaptive capacity, and health-related outcomes in a mountainous, climate-vulnerable population.

Conditions

  • Climate Change
  • Health Behavior / Well-Being
  • Disaster Planning

Intervention / Treatment

  • Other: Community Interventions
  • Other: Primary Healthcare Intervention

Primary Outcome Measures

  • Household disaster resilience (DRI) (At baseline and endline (12 month))
    Household disaster resilience will be assessed using the Disaster Resilience Index (DRI), a validated multidimensional composite measure of a household's ability to withstand, adapt to, and recover from shocks. The DRI comprises three domains: Coping Capacity, reflecting baseline resources and conditions that enable immediate response; Adaptive Capacity, capturing the ability to adjust and respond effectively through access to systems, resources, and support; and Transformative Capacity, measuring longer-term potential to learn, improve, and strengthen resilience over time. The score ranges from 0 to 1, with higher values indicating greater household resilience.

Countries

Pakistan

Locations and Investigators

  • Aga Khan University, Karachi, Pakistan (Recruiting)
    • Dr. Jai Kumar Das, PhD
    • Akber Ali, Masters
    • Dr. Jai Kumar Das, PhD (Principal Investigator)