Interventional Recruiting
NCT07740447 on ClinicalTrials.gov
Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics
Official title: Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on Targeted Metabolomics in Gingival Crevicular Fluid
- Sponsor: University of Catania
- Enrollment: 60 (Estimated)
- Study start: 2026-05-04 (Actual)
- Primary completion: 2026-11-16 (Estimated)
- Study completion: 2026-12-18 (Estimated)
- Allocation: Randomized
- InterventionModel: Parallel
- Masking: Double (Investigator, Outcomes Assessor)
- PrimaryPurpose: Treatment
Brief Summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid
Conditions
- Periodontitis
Intervention / Treatment
- Other: Probing depth reduction
Primary Outcome Measures
-
Probing pocket depth
(6 months)
Reduction in Probing Pocket Depth after treatment
Countries
Italy
Locations and Investigators
-
AOU Policlinico G. Rodolico, Catania, Italy (Recruiting)
- Gaetano Isola
- Rosalia Leonardi