Basil Britto Xavier

Infectiology — University Medical Center Groningen, Netherlands

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Basil Britto Xavier University Medical Center Groningen Netherlands
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Infectiology

Subspecialties: Genetics - Public Health - Critical Care

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Short Biography

A scientist with an impressive tenure of over 20 years, I have devoted my career to the intersection of microbiology, molecular biology, next-generation sequencing (NGS), and bioinformatics, focusing on groundbreaking applications in public health, antimicrobial resistance (AMR), and personalized medicine. With my educational foundation rooted in a Ph.D. in Medical Sciences, MA in Bioethics, and dual master's degrees in Biology and Microbiology, my passion for continuous learning is further complemented by multiple certifications in AI, NGS, and bioinformatics. Currently as a Senior Scientific Research Scientist at University Medical Center Groningen, where I contribute to the EU project DRAIGON, which represents a pioneering fusion of AI and genomic data to anticipate patterns of antimicrobial resistance. My scholarly endeavors have culminated in numerous publications, a patent, and a suite of grants and scholarships that underscore my commitment to scientific excellence. At the core of my professional mission is the ambition to harness the power of NGS technologies to revolutionize diagnostic techniques for multi-drug-resistant pathogens and to inform decisions in therapeutics - all while seeking out avant-garde methodologies to stem the tide of AMR globally. The amalgamation of my diverse skills in NGS, AMR, molecular biology, microbiology and bioinformatics are not only paramount in advancing our institutional capabilities but are essential to persevering in the global fight against antibiotic resistance. I am constantly striving to protect public health and ensure the well-being of diverse communities around the world. Highlight: "Basil Britto Xavier is a leading molecular microbiologist and genomics researcher specializing in antimicrobial resistance (AMR). He is internationally recognized for the landmark discovery of the mcr-2 colistin resistance gene and the vanP vancomycin resistance gene in Enterococcus. His seminal work on Nitrofurantoin resistance mechanisms and the development of the pLIN (Plasmid Lineage) classification system has transformed high-resolution pathogen tracking. Currently based at the University of Antwerp, his research integrates NGS, AI, and molecular biology to develop next-generation diagnostics for global health."

Organizations

Career arc: 2012 - 2026

Source: PubMed

University of Antwerp

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 99

Citations

Citations: 5 028 1st author: 9 Last author: 5 Unique author: 0


Best Journals

Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Global patterns and temporal evolution of fusidic acid resistance in Staphylococcus aureus: a genomic analysis of 2,701 resistant isolates spanning six decades.
staphylococcus, fusidic acid, staphylococcus aureus, communicable diseases
Int J Infect Dis20260
Genomic surveillance reveals long-term endemicity and outbreak potential of Klebsiella pneumoniae sequence type 48 in a German hospital and its global context.
genomics, multiple chronic conditions, genome, phylogeny, klebsiella, clone cells, virulence, klebsiella pneumoniae
Microb Genom20260
Urosepsis by multidrug-resistant Nakaseomyces glabratus with non-functional Erg3 and Erg11-do collateral sensitivity and a unique mode of action make nitroxoline a viable UTI antifungal?
urinary tract, pharmaceutical preparations, drug resistance, multiple, flucytosine, urinary tract infections, mycoses, therapeutics, drug collateral sensitivity, mutation, infections
mBio20260
Reinfection and ceftriaxone tolerance in a clinical case of recurrent gonorrhoea: a case report supported by in vitro and in vivo models.
research design, growth, treatment failure, cell biology, ceftriaxone, reinfection, infections
Front Cell Infect Microbiol20260
Phenotypic convergence and collateral susceptibility development in Pseudomonas aeruginosa under antibiotic exposure in ICU patients.
multiple chronic conditions, pseudomonas, pseudomonas aeruginosa, therapeutics, intensive care units
NPJ Antimicrob Resist20260

Clinical Studies 2

Sources: ClinicalTrials, EU CTIS

Synthesis

By phase:

N/A 1
Phase 3 1

By status:

Completed 2

By type:

Interventional 1
Observational 1

By Monocentric/Multicentric:

monocentric 1
multicentric2to4 0
multicentric5to9 0
multicentricup10 1

Main Topics

Cohort/Consortium Investigators 3

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