David Laplaud, MD, PhD is an expert in Neurology at Centre Hospitalier Universitaire de Nantes (France). As of October 2026, ScienceLeadR ranks David Laplaud in the top 1% of experts worldwide for Multiple Sclerosis and Autoimmune Diseases. David Laplaud has authored 362 publications, the most recent in 2026, and is an investigator in 37 clinical trials, 11 of them ongoing. SLR score: 1,528 (community average: 125). How the SLR is computed.

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David Laplaud, MD, PhD Centre Hospitalier Universitaire de Nantes France
1 528 ScienceLeadR Reputation 1528
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Neurology

Subspecialties: Immunology - Public Health - Internal Medicine

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Expert Rankings

Top experts on the MeSH terms this expert works on

Organizations

Career arc: 2000 - 2026

Source: PubMed

Centre d'Investigation Clinique de Nantes

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 362

Citations

Citations: 15 488 1st author: 19 Last author: 39 Unique author: 4


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Serum GFAP and Age Accurately Distinguish AQP4-IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack.
PMID 42798289 — multiple sclerosis, serum, probability, biomarkers, neuromyelitis optica, diagnosis, nervous system diseases
Eur J Neurol20260
Anti-CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non-Active Multiple Sclerosis.
PMID 42596034 — sclerosis, multiple sclerosis, aged, therapeutics, nervous system diseases, infections
Ann Clin Transl Neurol20260
A multi-outcome prognostic score for therapeutic responses in multiple sclerosis.
PMID 42481360 — registries, sclerosis, multiple sclerosis, brain, multiple chronic conditions, therapeutics, wounds and injuries, neurology
Rev Neurol (Paris)20260
Mapping of class II HLA restriction of SepSecS-specific CD4 T cell epitopes in autoimmune hepatitis.
PMID 42398735 — cells, hepatitis, autoimmune, epitopes, algorithms, cell line, t-lymphocytes, epitopes, t-lymphocyte, autoantigens, hepatitis
JHEP Rep20260
Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.
PMID 42377966 — cells, sclerosis, multiple sclerosis, blood, lymphocytes, brain, adaptive immunity, wounds and injuries, neurology, immunology
Brain20260

Clinical Studies 37

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 4

By phase:

Phase 3 23
N/A 11
Phase 1 1
Phase 2 1
Phase 4 1

By status:

Completed 15
Recruiting 7
Active not recruiting 6
Unknown 4
Not yet recruiting 3
Terminated 2

By type:

Interventional 31
Observational 6

By Monocentric/Multicentric:

monocentric 7
multicentric2to4 0
multicentric5to9 1
multicentricup10 29

Main Topics

Cohort/Consortium Investigators 15

Ongoing Clinical Trials

11 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
A Study Evaluating the Patient Perspective of the Physical Impact of Multiple Sclerosis and Providing Continued Access to Treatment in Patients with Multiple Sclerosis Previously Enrolled in a Genentech and or F Hoffmann La Roche Ltd Sponsored Study and without Access to A Post Trial Access Program
2023-507633-21-01 — sclerosis, multiple sclerosis, therapeutics
Phase 3Not yet recruiting2024
LONG TERM EFFECTIVENESS AND SAFETY EVALUATION OF OCRELIZUMAB IN FRENCH PATIENTS WITH PROGRESSIVE MS CONSONANCE EXTENSION STUDY
2024-516433-13-00 — safety
Phase 3Recruiting2024
A Rollover Study to Evaluate the Long Term Safety and Efficacy of Ocrelizumab In Patients with Multiple Sclerosis
2023-505974-14-00 — sclerosis, multiple sclerosis, safety
Phase 3Active not recruiting2022
PRIMUS Real World Usage for Real World Evidence of CDSS Use in Multiple Sclerosis
NCT07647952 — sclerosis, multiple sclerosis, multiple chronic conditions, decision support systems, clinical, therapeutics, software, multiple sclerosis, relapsing-remitting, medical devices
N/ANot yet recruiting2026
Disease Modifying Therapies Withdrawal in Inactive Relapsing remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS Therapies Withdrawal IN Relapsing Multiple Sclerosis)
NCT06663189 — glatiramer acetate, depression, sclerosis, multiple sclerosis, quality of life, spinal cord, disability evaluation, dimethyl fumarate, acetates, aged, fumarates, therapeutics, random allocation, multiple sclerosis, relapsing-remitting, infections, spine
Phase 3Not yet recruiting2025

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