Prof Fabrice Barlesi is an expert in Oncology at Institut Gustave Roussy (France). As of October 2026, ScienceLeadR ranks Fabrice Barlesi in the top 1% of experts worldwide for Bronchial Neoplasms, Lung Neoplasms and Thoracic Neoplasms. Fabrice Barlesi has authored 1,046 publications, the most recent in 2026, and is an investigator in 90 clinical trials, 13 of them ongoing. SLR score: 5,030 (community average: 125). How the SLR is computed.

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Prof Fabrice Barlesi Institut Gustave Roussy France
5 030 ScienceLeadR Reputation 5030
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Oncology

Subspecialties: Pulmonology - Biochemistry - Immunology

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Organizations

Career arc: 2001 - 2026

Source: PubMed

Institut Gustave Roussy

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 1046

Citations

Citations: 82 688 1st author: 118 Last author: 139 Unique author: 12


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Access to early-phase oncology trials: Trajectories and outcomes of more than 26,000 patients referred to a high-volume phase I unit.
PMID 42762559 — cells, pharmaceutical preparations, neoplasms, therapeutics
Eur J Cancer20260
Plain language summary of the KRYSTAL-12 study results: adagrasib for non-small cell lung cancer with KRAS G12C mutations.
PMID 42745627 — cells, language, lung, neoplasms, carcinoma, non-small-cell lung, lung neoplasms, small cell lung carcinoma, mutation
Future Oncol20260
Adjuvant alectinib versus chemotherapy in resected ALK-positive non-small-cell lung cancer (ALINA): health-related quality-of-life and safety outcomes from a randomised, open-label, phase 3 trial.
PMID 42636834 — cells, quality of life, lung, disease-free survival, safety, blood, neoplasms, carcinoma, non-small-cell lung, drug therapy, drug-related side effects and adverse reactions, lung neoplasms, small cell lung carcinoma, therapeutics, chemotherapy
Lancet Oncol Top journal20260
Patient-reported outcomes with adagrasib in KRYSTAL-12.
PMID 42624145 — patient reported outcome measures
Lancet Top journal20260
Bridging evidence and practice: international multidisciplinary consensus on non-metastatic NSCLC.
PMID 42532338 — research design, neoplasms, carcinoma, non-small-cell lung, uncertainty, therapeutics, rna
J Thorac Oncol20260

Clinical Studies 90

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 3

By phase:

Phase 3 36
Phase 2 26
N/A 11
Phase 1 7
Phase 1/Phase 2 6
Phase 2/Phase 3 3
Phase 4 1

By status:

Completed 59
Active not recruiting 12
Recruiting 8
Terminated 8
Unknown 3

By type:

Interventional 85
Observational 5

By Monocentric/Multicentric:

monocentric 13
multicentric2to4 1
multicentric5to9 3
multicentricup10 73

Main Topics

Cohort/Consortium Investigators 1

Ongoing Clinical Trials

13 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
Study of pre and post surgery treatment with IPH5201 and durvalumab in participants with lung cancer (MATISSE)
2023-507778-42-00 — cells, lung, neoplasms, carcinoma, non-small-cell lung, lung neoplasms, small cell lung carcinoma, neoadjuvant therapy, therapeutics
Phase 2Recruiting2023
Rollover study for participants who are currently being treated with and are continuing to benefit from opnurasib as a single agent or in combination with other study treatments
2025-523537-26-00 — cells, lung, neoplasms, multiple chronic conditions, carcinoma, non-small-cell lung, lung neoplasms, small cell lung carcinoma, therapeutics, mutation
Phase 1/Phase 2Recruiting2026
Study of Adagrasib plus Pembrolizumab plus Chemotherapy vs Placebo plus Pembrolizumab plus Chemotherapy in Participants with Previously Untreated Locally Advanced or Metastatic Non squamous NSCLC with KRAS G12C Mutation (KRYSTAL 4)
2024-515698-85-00 — cells, lung, neoplasms, carcinoma, non-small-cell lung, drug therapy, lung neoplasms, small cell lung carcinoma, mutation, chemotherapy
Phase 3Recruiting2025
A Global Study to Assess the Effects of Durvalumab with Oleclumab or Durvalumab with Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non Small Cell Lung Cancer (PACIFIC 9)
2023-503999-24-00 — cells, lung, neoplasms, carcinoma, non-small-cell lung, lung neoplasms, small cell lung carcinoma, therapeutics
Phase 3Active not recruiting2022
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C mutant Non Small Cell Lung Cancer
NCT06890598 — cells, lung, safety, neoplasms, carcinoma, non-small-cell lung, immunotherapy, lung neoplasms, small cell lung carcinoma, carcinoma
Phase 3Recruiting2025

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