Frédéric Di Fiore is an expert in Oncology at Centre Henri Becquerel (France). As of October 2026, ScienceLeadR ranks Frédéric Di Fiore in the top 1% of experts worldwide for Carcinoma, Gastrointestinal Neoplasms and Intestinal Neoplasms. Frédéric Di Fiore has authored 243 publications, the most recent in 2026, and is an investigator in 51 clinical trials, 23 of them ongoing. SLR score: 1,229 (community average: 125). How the SLR is computed.

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Frédéric Di Fiore Centre Henri Becquerel France
1 229 ScienceLeadR Reputation 1229
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Oncology

Subspecialties: Gastroenterology - Immunology - Hepatology

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Organizations

Career arc: 2000 - 2026

Source: PubMed

INSERM

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 243

Citations

Citations: 13 848 1st author: 22 Last author: 22 Unique author: 1


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Mucosal tissue cues shape B cell memory through the IgA BCR.
PMID 42467745 — cells, immunoglobulin a, tissues, mucous membrane, memory, b-lymphocytes, infections, memory b cells
Sci Immunol20261
Impact of postoperative chemotherapy in patients resected for esophagogastric adenocarcinoma with major pathological response after preoperative chemotherapy: a study from the FREGAT database.
PMID 42466102 — neoplasms, adenocarcinoma, drug therapy, chemotherapy
Ther Adv Med Oncol20260
Addition of ipilimumab to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma (PRODIGE 81-FFCD 2101-TRIPLET HCC): phase 2 results from a randomised, multicentre, open-label, phase 2-3 trial.
PMID 42330996 — liver diseases, hypertension, carcinoma, hepatocellular, bevacizumab, transaminases, drug-related side effects and adverse reactions, therapeutics, ipilimumab, gastrointestinal diseases
Lancet Gastroenterol Hepatol Top journal20265
Automatic lesion segmentation in ⁶⁸Ga-PSMA PET/CT and ¹⁷⁷Lu-PSMA SPECT/CT: added value of PET-guided SPECT in a bicentric study.
PMID 42387196 — single photon emission computed tomography computed tomography, neoplasms, prostate, positron emission tomography computed tomography, neoplasm metastasis, tomography, emission-computed, single-photon, prostatic neoplasms, therapeutics
EJNMMI Res20261
Circulating tumour DNA in patients with colorectal cancer undergoing curative-intent LIver MEtastases Surgery in France: a prospective, multicentre GERCOR G-118 CLIMES PRODIGE 77 cohort study protocol.
PMID 42379715 — neoplasms, cohort studies, drug therapy, liver, neoplasm metastasis, therapeutics, colorectal neoplasms, dna, prognosis, chemotherapy
BMJ Open20260

Clinical Studies 51

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 7

By phase:

Phase 2 23
Phase 3 14
N/A 9
Phase 2/Phase 3 5

By status:

Recruiting 20
Completed 17
Not yet recruiting 5
Active not recruiting 3
Terminated 3
Unknown 3

By type:

Interventional 47
Observational 4

By Monocentric/Multicentric:

monocentric 6
multicentric2to4 1
multicentric5to9 3
multicentricup10 41

Main Topics

Ongoing Clinical Trials

23 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
ENGIC 06 (PRODIGE 114) FFCD 2401 FRUQUITAS Randomized phase III trial to compare trifluridine tipiracil Fruquintinib versus trifluridine tipiracil alone for metastatic oeso gastric adenocarcinoma
2025-522395-92-00 — trifluridine, adenocarcinoma
Phase 3Recruiting2025
A clinical study of MK 1084 with targeted therapy and chemotherapy in people with colorectal cancer (MK 1084 012)
2024-517232-22-00 — safety, cetuximab, neoplasms, bevacizumab, drug therapy, therapeutics, colorectal neoplasms, chemotherapy
Phase 3Recruiting2025
Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Previously Untreated Unresectable or Metastatic Colorectal Cancer
2025-523224-45-00 — pharmaceutical preparations, neoplasms, bevacizumab, drug therapy, colorectal neoplasms, chemotherapy
Phase 2/Phase 3Not yet recruiting2026
ENGIC 01 COLOSOTO A single arm phase II study evaluating 5 fluorouracil plus Panitumumab (anti EGFR) and Sotorasib (KRAS G12C inhibitor) in first line treatment of patients non eligible for a doublet triplet chemotherapy with advanced unresectable KRAS G12C mutated colorectal adenocarcinoma
2024-514030-20-00 — neoplasms, adenocarcinoma, drug therapy, fluorouracil, panitumumab, therapeutics, colorectal neoplasms, chemotherapy
Phase 2Recruiting2025
PRODIGE 88 CIRCULATE PAC Phase III multicentric open label randomized study to investigate the efficacy of chemotherapy in patients with positive ctDNA after surgery and adjuvant chemotherapy for a high risk stage II and stage III Colorectal Cancer
2023-505046-26-00 — neoplasms, colon, drug therapy, chemotherapy, adjuvant, colorectal neoplasms, chemotherapy, carcinoma
Phase 3Recruiting2026

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