Frederick J Raal is an expert in Cardiology at University of the Witwatersrand (South Africa). As of October 2026, ScienceLeadR ranks Frederick J Raal in the top 1% of experts worldwide for Hypercholesterolemia, Hyperlipidemias and Dyslipidemias. Frederick J Raal has authored 471 publications, the most recent in 2026, and is an investigator in 23 clinical trials. SLR score: 2,085 (community average: 125). How the SLR is computed.

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Frederick J Raal University of the Witwatersrand South Africa
2 085 ScienceLeadR Reputation 2085
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Cardiology

Subspecialties: Endocrinology - Biochemistry - Public Health

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

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Short Biography

Frederick J. Raal, MBBCh (cum laude), FRCP, FRCPC, FCP(SA), Cert Endo, MMED, PhD, DSC

Director, Carbohydrate and Lipid Metabolism Research Unit Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

Professor Raal is a Distinguished Professor in the Division of Endocrinology and Metabolism, as well as Director of the Carbohydrate and Lipid Metabolism Research Unit, University of the Witwatersrand, Johannesburg, South Africa.

He is a NRF A-rated scientist and has authored or co-authored over 400 original articles and book chapters and has reviewed for several international journals including the New England Journal of Medicine, the Lancet, Circulation, and Atherosclerosis. He is on the Editorial Board of Atherosclerosis, a co-editor for Current Opinion in Lipidology and is a Board member of the International Atherosclerosis Society.

Professor Raal is particularly interested in lipids and lipid disorders and has been integrally involved in the management of familial dyslipidaemia, particularly heterozygous and homozygous familial hypercholesterolaemia (FH). The major focus of his research remains the clinical, biochemical, genetic and therapeutic management of this condition and he continues to conduct studies with novel therapies such as PCSK9-inhibitors and ANGPTL3-inhibitors in this patient group.

Organizations

Career arc: 1985 - 2026

Source: PubMed

University of the Witwatersrand

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 471

Citations

Citations: 30 882 1st author: 87 Last author: 120 Unique author: 14


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Reducing LDL-Cholesterol Burden in Homozygous Familial Hypercholesterolemia: The Earlier, The Lower, The Longer, The Better.
PMID 42954708 — hyperlipoproteinemia type ii, cholesterol, ldl, cholesterol, atherosclerosis, hypercholesterolemia, homozygous familial hypercholesterolemia
JACC Case Rep20260
Homozygous familial hypercholesterolaemia: insights from the Global HICC Registry.
PMID 42149947 — registries, cholesterol, ldl, lipoproteins, cardiovascular diseases, cardiology, cholesterol, sex, diagnosis, therapeutics
Eur Heart J Top journal20260
Lipoprotein(a)-dependent cardiovascular risk in different populations: are thresholds the same?
PMID 42856082 — lipoproteins, cohort studies, lipoprotein(a)
Ann Med20260
Serum lipids and outcomes of COVID-19 patients admitted to a tertiary hospital in Johannesburg, South Africa.
PMID 42563655 — tertiary care centers, fasting, mortality, cholesterol, ldl, serum, lipoproteins, hospital mortality, cholesterol, covid-19, intensive care units, ventilation, plasma
S Afr Med J20260
Andes virus associated hantavirus cardiopulmonary syndrome and repurposing lipid medications to calm down the cytokine storm.
PMID 42468739 — cytokines, ezetimibe, cytokine release syndrome, orthohantavirus, viruses, satellite viruses, hydroxymethylglutaryl-coa reductase inhibitors, communicable diseases
Int J Infect Dis20260

Clinical Studies 23

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 2

By phase:

Phase 3 13
N/A 3
Phase 2 3
Phase 2/Phase 3 2
Phase 4 2

By status:

Completed 19
Recruiting 2
Enrolling by invitation 1
Terminated 1

By type:

Interventional 20
Observational 3

By Monocentric/Multicentric:

monocentric 2
multicentric2to4 1
multicentric5to9 2
multicentricup10 18

Main Topics

Cohort/Consortium Investigators 1

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