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Frank Tacke is an expert in Hepatology at Charité - University Medicine Berlin (Germany). As of October 2026, ScienceLeadR ranks Frank Tacke in the top 1% of experts worldwide for MASH, Liver Cirrhosis and Critical Illness. Frank Tacke has authored 1,271 publications, the most recent in 2026, and is an investigator in 13 clinical trials, 5 of them ongoing. SLR score: 5,067 (community average: 125). How the SLR is computed.

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Frank Tacke Charité - University Medicine Berlin Germany
5 067 ScienceLeadR Reputation 5067

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Hepatology

Subspecialties: Gastroenterology

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Expert Rankings

Top experts on the MeSH terms this expert works on

Organizations

Career arc: 2001 - 2026
Source: PubMed

Charité - University Medicine Berlin

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 1271

Citations

Citations: 77 446 1st author: 77 Last author: 354 Unique author: 14

Main journals

J Hepatol 189
Z Gastroenterol 135
Hepatology 56
Liver Int 31
J Clin Med 28

Best Journals

J Hepatol 66
Nat Rev Gastroenterol Hepatol 12
Nature 11

Breakdown by type

Click a legend label to hide or show it in the chart.

Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
The dynamic spectrum of steatotic liver disease: the global perspective.
PMID 42567912 — liver diseases, fibrosis, liver, therapeutics, alcohol drinking		Nat Rev Gastroenterol Hepatol Top journal20260
New paradigms in Hepatitis D: screening, treatment, and the path to cure.
PMID 42933498 — liver diseases, hepatitis d, antigens, surface, hepatitis, chronic, therapeutics, antiviral agents, hepatitis		Semin Liver Dis20260
Altered OXPHOS potential in ascites immune cells is linked to CD4 T-cell exhaustion and a higher risk of spontaneous bacterial peritonitis in cirrhosis.
PMID 42903199 — cells, peritonitis, blood, mitochondria, t-lymphocytes, ascites		Front Immunol20260
Epithelial NF-κB shapes protective Treg cell responses to restrain intestinal inflammation.
PMID 42901926 — cells, t-lymphocytes, regulatory, colitis, communication, tissues		Nat Commun20260
Training the next generation of hepatologists for the cardiovascular-kidney-metabolic era.
PMID 42888296 — kidney, gastroenterologists		Nat Rev Gastroenterol Hepatol Top journal20260

Clinical Studies 13

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 4

By phase:

N/A 5
Phase 3 4
Phase 2 3
Phase 4 1

By status:

Completed 4
Recruiting 4
Terminated 3
Not yet recruiting 1
Unknown 1

By type:

Interventional 9
Observational 4

By Monocentric/Multicentric:

monocentric 3
multicentric2to4 1
multicentric5to9 0
multicentricup10 9

Main Topics

Cohort/Consortium Investigators 6

Ongoing Clinical Trials

5 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
Study to learn about the safety of fazirsiran and if it can help people with alpha 1 antitrypsin liver disease with mild liver scarring (fibrosis)
2023-504198-19-00 — liver diseases, safety, fibrosis, alpha 1-antitrypsin deficiency, liver, therapeutics, alpha 1-antitrypsin		Phase 3Not yet recruiting2024
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha 1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
NCT06165341 — liver diseases, injections, safety, fibrosis, alpha 1-antitrypsin deficiency, liver, therapeutics, alpha 1-antitrypsin		Phase 3Recruiting2024
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha 1 Antitrypsin Protein
NCT05677971 — liver diseases, injections, safety, saline solution, fibrosis, alpha 1-antitrypsin deficiency, liver, therapeutics, alpha 1-antitrypsin		Phase 3Recruiting2023
International Wilson s Disease Patient Registry (iWilson Registry)
NCT05239858 — registries, trientine, hepatolenticular degeneration, penicillamine, history		N/ARecruiting2022
Validation of CAGIB Score for In hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding
NCT04662918 — mortality, hemorrhage, liver cirrhosis, gastrointestinal hemorrhage, hospital mortality, liver		N/ARecruiting2022

LeadR Networks

Main global connection map

Sources: PubMed, OpenAlex, ClinicalTrials, EU CTIS