George D Demetri is an expert in Oncology at Dana-Farber Cancer Institute (United States). As of June 2026, ScienceLeadR ranks George D Demetri in the top 1% of experts worldwide for Sarcoma and Gastrointestinal Neoplasms. George D Demetri has authored 611 publications, the most recent in 2026, and is an investigator in 41 clinical trials, 2 of them ongoing. SLR score: 2,773 (community average: 125). How the SLR is computed.

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George D Demetri Dana-Farber Cancer Institute United States
2 773 ScienceLeadR Reputation 2773
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Oncology

Subspecialties: Biochemistry - Genetics

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Expert Rankings

Top experts on the MeSH terms this expert works on

Organizations

Career arc: 1986 - 2026

Source: PubMed

Dana-Farber Cancer Institute

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 611

Citations

Citations: 80 656 1st author: 65 Last author: 172 Unique author: 33


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial.
PMID 42191879 — confidence intervals, growth, gastrointestinal stromal tumors, oxidoreductases, succinate dehydrogenase, molecular biology, neoplasms, biopsy, receptors, growth factor, receptors, fibroblast growth factor, fibroblasts, exome, fibroblast growth factors
Nat Med Top journal20260
Tazemetostat, an EZH2 inhibitor, in solid tumors harboring SWI/SNF alterations: a phase II basket study.
PMID 41882006 — sarcoma, synovial, biological science disciplines, neoplasms, rhabdoid tumor, sarcoma, chordoma, therapeutics
Nat Commun20260
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity.
PMID 41564157 — glucagon-like peptide 1, cells, cell plasticity, liposarcoma, neoplasms, histology
Sci Transl Med20260
A Phase 2 Study of the Eribulin in Patients with Metastatic Angiosarcoma and Epithelioid Hemangioendothelioma (EHE).
PMID 41481257 — hemangiosarcoma, hemangioendothelioma, neoplasms, sarcoma, therapeutics, hemangioendothelioma, epithelioid
Clin Cancer Res20260
Validation of an AI-enabled exome/transcriptome liquid biopsy platform for early detection, MRD, disease monitoring, and therapy selection for solid tumors.
PMID 40596693 — blood, transcriptome, neoplasms, multiple chronic conditions, biopsy, machine learning, exome, therapeutics, learning, artificial intelligence, tissues, liquid biopsy
Sci Rep20250

Clinical Studies 41

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 1 Study Chair: 6

By phase:

Phase 2 18
Phase 3 11
Phase 1 7
N/A 5

By status:

Completed 34
Active not recruiting 4
Approved for Marketing 1
No longer available 1
Terminated 1

By type:

Interventional 36
Observational 3
Expanded Access 2

By Monocentric/Multicentric:

monocentric 9
multicentric2to4 7
multicentric5to9 7
multicentricup10 18

Main Topics

Cohort/Consortium Investigators 5

Ongoing Clinical Trials

2 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)
NCT06088290 — leiomyosarcoma, doxorubicin, neoplasms, therapeutics
Phase 3Active not recruiting2023
Testing the Anti cancer Drug Rogaratinib (BAY 1163877) for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1 4) and in Patients With SDH deficient Gastrointestinal Stromal Tumor (GIST)
NCT04595747 — cells, research design, growth, blood, gastrointestinal stromal tumors, pharmaceutical preparations, tomography, positron-emission tomography, neoplasms, magnetic resonance imaging, biopsy, positron emission tomography computed tomography, sarcoma, receptors, growth factor, receptors, fibroblast growth factor, specimen handling, fibroblasts, therapeutics, fibroblast growth factors
Phase 2Active not recruiting2021

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