Guanzhang Li, MD, PhD is an expert in Neurosurgery at Beijing Tiantan Hospital (China). As of September 2026, ScienceLeadR ranks Guanzhang Li in the top 1% of experts worldwide for Glioma. Guanzhang Li has authored 114 publications, the most recent in 2026, and is an investigator in 2 clinical trials, 2 of them ongoing. SLR score: 373 (community average: 125). How the SLR is computed.

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Guanzhang Li, MD, PhD Beijing Tiantan Hospital China
373 ScienceLeadR Reputation 373
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Neurosurgery

Subspecialties: Oncology - Neurology - Biochemistry

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Short Biography

Dr. Li is Principal Investigator in the Department of Molecular Neuropathology, Beijing Neurosurgical Institute; Associate Chief Neurosurgeon, Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; Head of the Innovative Immunotherapy R&D Platform, Beijing Engineering Research Center for Targeted Therapy and Cell Therapy of Nervous System Tumors.

Dr. Li have long been engaged in elucidating the mechanisms of therapeutic resistance in glioma stem cells and developing innovative therapies. He have secured 3 national-level grants​ (including the National Natural Science Foundation of China) and 2 provincial/ministerial-level grants​ (including the Beijing Outstanding Young Scientist Fund). As first/corresponding author (including co-first/corresponding), he have published 31 SCI-indexed papers​ in high-impact journals such as Cell Metabolism and Brain, including 2 ESI Highly Cited Papers. His total publication record comprises 91 SCI-indexed papers​ with 4,082 citations​ and an h-index of 30.

As a sub-principal investigator, Dr. Li have initiated 4 clinical trials, with 2 completed. He have contributed to 4 monographs​ and participated in formulating 3 international​ and 3 national clinical guidelines​ for glioma. He hold 12 Chinese invention patents, 1 utility model patent, 1 software copyright, 4 PCT patents, and have publicly disclosed 4 US patents​ and 4 European patents, with 4 invention patents successfully translated/commercialized​ via the China Technology Exchange.

His academic achievements have been recognized with the Best Invention Award​ (IFIA), the Grand Prix & Gold Medal​ (iENA Nuremberg), the Silver Award​ (National Postdoctoral Innovation Contest), and the Frontier Academic Achievement in the Capital. He have been honored as a National Outstanding Postdoctoral Innovator, selected for the Beijing Association for Science and Technology (BAST) Young Talent Program.

Organizations

Career arc: 2015 - 2026

Source: PubMed

Beijing Neurosurgical Institute

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 114

Citations

Citations: 3 868 1st author: 14 Last author: 2 Unique author: 0


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
An ambispective, observational real-world study of tumor-treating fields for treatment of Chinese patients with newly diagnosed or recurrent/progressive glioblastoma.
PMID 42211392 — skin, safety, neoplasms, glioblastoma, therapeutics
Neurooncol Adv20260
MET fusions and splicing variants in glioma: a landscape integrating clinical, pathological, and survival features.
PMID 41910014 — glioma, astrocytoma, neoplasms, multivariate analysis, glioblastoma, kaplan-meier estimate
J Pathol Clin Res20260
A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations.
PMID 41886621 — cells, glioma, neoplasms, algorithms, organoids, deep learning, glioblastoma, therapeutics, learning, mutation
Cancer Res20260
Metabolic Profiling Defines Glioblastoma Subtypes with Distinct Prognoses and Therapeutic Vulnerabilities.
PMID 41485080 — brain neoplasms, cells, genes, classification, glioblastoma, therapeutics, prognosis
Neuro Oncol20260
Updated Clinical practice guidelines for the management of adult diffuse gliomas.
PMID 41338443 — glioma, neoplasms, research, therapeutics
Cancer Lett20250

Clinical Studies 2

Sources: ClinicalTrials, EU CTIS

Synthesis

By phase:

Phase 1 1
Phase 1/Phase 2 1

By status:

Recruiting 2

By type:

Interventional 2

By Monocentric/Multicentric:

monocentric 2
multicentric2to4 0
multicentric5to9 0
multicentricup10 0

Main Topics

Ongoing Clinical Trials

2 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
A Clinical Trial of P134 Cells in Recurrent Glioblastoma
NCT07318818 — injections, cells, safety, pathology, glioblastoma, therapeutics, car-t cell
Phase 1/Phase 2Recruiting2026
Tris CAR T Cell Therapy for Recurrent Glioblastoma
NCT05577091 — cells, blood, lymphocytes, neoplasms, immunotherapy, drug-related side effects and adverse reactions, glioblastoma, therapeutics, t-lymphocytes, car-t cell
Phase 1Recruiting2023

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