José-Alain Sahel

Ophthalmology — Quinze-Vingts National Eye Hospital, France

LeadR Profile

José-Alain Sahel Quinze-Vingts National Eye Hospital France
4 107 ScienceLeadR Reputation 4107
Network Map

Ophthalmology

Subspecialties: Genetics - Neurology - Biochemistry

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Organizations

Career arc: 1980 - 2026

Source: PubMed

University of Pittsburgh Medical Center

could not re-read experiences after save", error); return null; } if (persistedEntries === null) { return null; } if (persistedEntries.length === 0 && sent.some((entry) => entry.isvisible !== false)) { console.warn(" re-read after save came back empty, keeping the edited entries"); return null; } this.state.current.experience = persistedEntries; const expected = this.yearsSignature(sent); const received = this.yearsSignature(persistedEntries.map((entry) => ({ isvisible: entry.isvisible, topresent: entry.topresent, year_start: entry.startperiod, year_stop: entry.endperiod }))); if (expected !== received) { console.error(" saved experiences were not persisted as sent", { sent: expected, received: received }); return false; } return true; }, async fetchExperiences() { const response = await $.ajax({ url: ajaxLoadUserData, type: "POST", data: { security: ajaxDataLoadUserData.security, data_to_load: "OrganizationHisto", } }); const parsedData = JSON.parse(response); if (parsedData.loaded === false || !parsedData.user_data || !Array.isArray(parsedData.user_data)) { return null; } return parsedData.user_data.map((value, index) => ({ company: value["name"], url: "", position: (value.hasOwnProperty("position") ? ( value["position"] ) : ( "" ) ), startperiod: value["year_start"], endperiod: value["year_stop"], topresent: (value.hasOwnProperty("topresent") ? ( value["topresent"] ) : ( false ) ), orgid: value["orgid"], isvisible: (value.hasOwnProperty("isvisible") ? ( value["isvisible"] ) : ( true ) ), description: "", tags: [], isOpen: false, ismain: (value.hasOwnProperty("ismain") ? ( value["ismain"] ) : ( (index === 0) ? true : false ) ) })); }, async loadDataOnMount() { this.loading = true; try { const experiences = await this.fetchExperiences(); this.loadFailed = experiences === null; if (experiences !== null) { this.state.current.experience = experiences; } } catch (error) { console.warn(" could not load experiences", error); this.loadFailed = true; } this.loading = false; } }, computed: { experience: { get() { return this.state.current.experience }, }, }, async mounted() { await this.loadDataOnMount() }, } }; })

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 1093

Citations

Citations: 37 622 1st author: 30 Last author: 169 Unique author: 15


Breakdown by type

Click a legend label to hide or show it in the chart.

Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Reprogramming translation for rare disease therapy: challenges posed by large genes.
genes, rare diseases, signal transduction, therapeutics
Signal Transduct Target Ther Top journal20260
High-Resolution and Multimodal Structural Phenotyping of Intermediate and Advanced Non-Neovascular Age-Related Macular Degeneration.
eye, macular degeneration, atrophy, phenotype, classification, multimodal imaging, lighting, retinaldehyde
Ophthalmol Sci20260
Distinct interactions between macular neovascularization and geographic atrophy: Growth dynamics and fellow-eye risk.
eye, growth, atrophy, eye diseases, geographic atrophy
Eur J Ophthalmol20260
Deep Learning-Based Automated Segmentation and Quantification of the Ellipsoid Zone and the RPE-Bruch's Membrane Complex in Healthy Subjects and in Geographic Atrophy.
eye, research design, atrophy, retina, healthy volunteers, deep learning, learning, artificial intelligence, retinaldehyde, membranes, geographic atrophy, bruch membrane
Diagnostics (Basel)20261
Histological findings after subretinal implantation of the PRIMA photovoltaic array in patients with geographic atrophy due to AMD.
eye, atrophy, retina, tissues, retinaldehyde, membranes, geographic atrophy
Ophthalmol Retina20260

Clinical Studies 18

Sources: ClinicalTrials, EU CTIS

Synthesis

Study Chair: 1

By phase:

N/A 12
Phase 1/Phase 2 3
Phase 3 3

By status:

Completed 10
Active not recruiting 3
Recruiting 3
Terminated 2

By type:

Interventional 10
Observational 8

By Monocentric/Multicentric:

monocentric 5
multicentric2to4 1
multicentric5to9 7
multicentricup10 5

Main Topics

Cohort/Consortium Investigators 11

Ongoing Clinical Trials

2 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
Promising ROd cone DYstrophy Gene therapY
NCT05748873 — retinal dystrophies, eye, retinitis, genes, cone dystrophy, retinal degeneration, safety, cone-rod dystrophies, eye diseases, retinitis pigmentosa, therapeutics, retinal diseases, retinaldehyde, mutation
Phase 1/Phase 2Active not recruiting2023
Universal Rare Gene Study A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease Causing Genetic Variants
NCT05589714 — retinal dystrophies, registries, retinitis, genes, natural history, retinal degeneration, rare diseases, retinitis pigmentosa, history, retinaldehyde
N/ARecruiting2023

LeadR Networks

Main global connection map