Laurent Castera
Laurent Castera is an expert in Genetics at Centre François Baclesse (France). Laurent Castera has authored 73 publications, the most recent in 2026, and is an investigator in 3 clinical trials, 2 of them ongoing. SLR score: 237 (community average: 125). How the SLR is computed.
LeadR Profile
Genetics
Subspecialties: Hepatology - Oncology - Gastroenterology
Main Topics
Publications and Clinical Studies
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Organizations
Career arc: 2010 - 2026
Number : 73
Citations
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Latest Publications
5 most recent indexed articles
Source: Pubmed
| Title | Journal | Year | Citations |
|---|---|---|---|
| Cancer risks for ATM variant heterozygotes. PMID 42052916 — heterozygote, pancreatic neoplasms, breast neoplasms, neoplasms, penetrance, breast, genetics, medical | Genet Med | 2026 | 0 |
| Comparative performance of a targeted next-generation sequencing assay against multiplexed digital PCR assays in detecting ERBB2, ESR1, and PIK3CA mutations in plasma circulating cell-free DNA from liquid biopsies. PMID 41072730 — cells, genes, high-throughput nucleotide sequencing, breast neoplasms, polymerase chain reaction, neoplasms, multiple chronic conditions, biopsy, cell-free nucleic acids, solutions, breast, dna, liquid biopsy, mutation, plasma | J Mol Diagn | 2025 | 0 |
| Long-term patient-derived ovarian cancer organoids closely recapitulate tumor of origin and clinical response. PMID 41057919 — pharmaceutical preparations, ovary, neoplasms, drug therapy, organoids, ovarian neoplasms, genomic instability, medical oncology, chemotherapy | J Exp Clin Cancer Res | 2025 | 6 |
| Decipher RNA isoform combinations from minigene splicing assays and massive parallel sequencing with MAGIC. PMID 40973179 — magic, protein isoforms, rna | Bioinformatics | 2025 | 0 |
| Bridging the Diagnostic Gap in Hereditary Cancers with Simple, Cost-Effective, High-Throughput RNA Splicing Analysis. PMID 40712994 — genes, neoplasms, ligation, rna splicing, rna | J Mol Diagn | 2025 | 1 |
Clinical Studies 3
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Ongoing Clinical Trials
2 ongoing trials started since 2021, where this expert is an investigator
Source: ClinicalTrials
| Study | Phase | Status | Start |
|---|---|---|---|
| Collection of Endometrial Cancer derived Organoids to Evaluate the Efficacy of PARP Inhibitors PENDOR Pilot Study NCT06603506 — pilot projects, pilots, poly(adp-ribose) polymerase inhibitors, blood, neoplasms, organoids, endometrial neoplasms | N/A | Recruiting | 2024 |
| HRD Tests for Ovarian cancER NCT06152731 — recombination, genetic, poly(adp-ribose) polymerase inhibitors, homologous recombination, ovary, neoplasms, drug therapy, ovarian neoplasms, therapeutics, chemotherapy, carcinoma | Phase 2 | Recruiting | 2024 |
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