Pascal Reynier
Pascal Reynier is an expert in Biochemistry at Centre Hospitalier Universitaire d'Angers (France). As of October 2026, ScienceLeadR ranks Pascal Reynier in the top 1% of experts worldwide for Optic Nerve Diseases, Mitochondrial Diseases and Eye Diseases, Hereditary. Pascal Reynier has authored 345 publications, the most recent in 2026, and is an investigator in 7 clinical trials, 3 of them ongoing. SLR score: 1,051 (community average: 125). How the SLR is computed.
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Biochemistry
Subspecialties: Neurology - Ophthalmology - Nutrition
Main Topics
Publications and Clinical Studies
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Organizations
Career arc: 1994 - 2026
Number : 345
Citations
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Latest Publications
5 most recent indexed articles
Source: Pubmed
| Title | Journal | Year | Citations |
|---|---|---|---|
| Plasma Lipid Remodeling across Preclinical Burden, Disease Onset, and Early Motor Severity in Huntington's Disease. PMID 42860925 — docosahexaenoic acids, palmitates, movement disorders, metabolomics, cost of illness, lipidomics, triglycerides, huntington disease, plasma, phospholipids | Mov Disord | 2026 | 0 |
| Low-level of mitochondrial DNA alterations during direct-acting antiviral treatment in leukocytes of people who inject drugs living with HCV. PMID 42852927 — safety, blood, pharmaceutical preparations, mitochondria, drug users, dna, mitochondrial, viruses, leukocytes, therapeutics, tissues, antiviral agents, hepatitis | Microbiol Spectr | 2026 | 0 |
| Phenotypic Variations in a Large Family with Dominant Optic Atrophy Related to a Novel OPA1 Deletion. PMID 42518794 — cells, atrophy, retina, optic atrophy, optic atrophy, autosomal dominant, visual acuity, ganglion cysts, retinaldehyde | Ophthalmol Sci | 2026 | 0 |
| Methionine restriction plus vitamin B12 antagonism overcomes methionine independence for cancer therapy. PMID 42425191 — cells, growth, vitamins, neoplasms, methionine, vitamin b 12, research, therapeutics | Cancer Lett | 2026 | 0 |
| High-Resolution Imaging Reveals Mitochondrial Protein Imbalance in Sperm of Oligoasthenospermic Men. PMID 42112582 — mitochondrial proteins, reproduction, fertility, embryonic development, infertility, mitochondria, microscopy, infertility, male, fetal development, spermatozoa | Mol Reprod Dev | 2026 | 0 |
Clinical Studies 7
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Cohort/Consortium Investigators 2
Ongoing Clinical Trials
3 ongoing trials started since 2021, where this expert is an investigator
Source: ClinicalTrials
| Study | Phase | Status | Start |
|---|---|---|---|
| Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber s Hereditary Optic Neuropathy NCT07258667 — pilot projects, cells, research design, pilots, mitochondrial diseases, vision, ocular, safety, atrophy, niacinamide, optic atrophy, hereditary, leber, vitamins, optic atrophies, hereditary, optic atrophy, retinal ganglion cells, optic nerve, tomography, optical coherence, therapeutics, ganglion cysts, retinaldehyde, optic nerve diseases, mutation | Phase 1 | Not yet recruiting | 2026 |
| Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (M tabOCT) NCT06682819 — atrophy, optic atrophy, hereditary, leber, tomography, optic atrophies, hereditary, optic disk, optic atrophy, nerve fibers, optic nerve, healthy volunteers, dna, mitochondrial, metabolomics, retinaldehyde, optic nerve diseases, mutation | N/A | Recruiting | 2023 |
| Tolerance and Efficacy Nicotinamide (Vitamin B3) in Dominant Optic Atrophy OPA1 NCT06007391 — pilot projects, pilots, atrophy, niacinamide, vitamins, pathology, glaucoma, open-angle, mitochondria, optic atrophy, optic nerve, optic atrophy, autosomal dominant, glaucoma, metabolomics, therapeutics, optic nerve diseases | Phase 2/Phase 3 | Active not recruiting | 2024 |
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