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Journal Article Epublish 5 citations

PubMed: 34027128 DOI: 10.1002/hsr2.301

The effect of zinc supplementation on fatigue among elderly community dwellers: A parallel clinical trial.

Health Sci Rep 4(2):e301

Authors: Abolfazl Afzali, Shahrbanoo Goli, Alireza Moravveji, Hossein Bagheri, Seyedmohammad Mirhosseini, Hossein Ebrahimi

Affiliations

  • Student Research Committee, School of Nursing & Midwifery Shahroud University of Medical Sciences Shahroud Iran.
  • Department of Epidemiology and Biostatistics, School of Public Health Shahroud University of Medical Sciences Shahroud Iran.
  • Social Determinants of Health (SDH) Research Center Kashan University of Medical Sciences Kashan Iran.
  • School of Nursing & Midwifery Shahroud University of Medical Sciences Shahroud Iran.
  • Student Research Committee, School of Nursing and Midwifery Mashhad University of Medical Sciences Mashhad Iran.
  • Center for Health Related Social and Behavioral Sciences Research Shahroud University of Medical Sciences Shahroud Iran.

Abstract

BACKGROUND AND AIMS

Fatigue is one of the most common complaints of the elderly. This study was conducted to assess the effect of zinc supplements on fatigue among the elderly.

METHODS

This randomized clinical trial was conducted on 150 elderly aged ≥60 years who were recruited from the health centers (Kashan, Iran) with a convenience sampling method. Participants were allocated to intervention and control groups by block randomization. Participants in the intervention group received a daily dose of 30 mg of zinc supplement for 70 days; meanwhile, in the control group, no intervention was performed. The level of fatigue was measured by the multidimensional fatigue inventory before and after the intervention. Both groups were homogeneous in terms of demographic variables, fatigue, and serum zinc level before the intervention. The significance level was considered as 0.05 in all tests.

RESULTS

Zinc supplementation significantly reduced fatigue (mean difference: -10.41 vs 1.37,  < .001) and increased serum zinc level (mean difference: 14.22, vs -0.57,  < .001) compared to the control group.

CONCLUSION

Consumption of zinc supplements for the elderly is recommended to overcome fatigue.

MeSH

Aged, Aging, Geriatric Nursing, Fatigue, Serum

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