Journal Article Ppublish 14 citations
PubMed: 35686205 DOI: 10.46234/ccdcw2022.081
Preliminary Study of the Protectiveness of Vaccination Against the COVID-19 in the Outbreak of VOC Omicron BA.2 - Jilin City, Jilin Province, China, March 3-April 12, 2022.
China CDC Wkly 4(18):377-380
Authors: Xuebin Fan, Shan Lu, Lu Bai, Haican Liu, Junshao Fu, Xiaoxun Jin, Yulong He, Jinxing Lu, Xiaoping Dong
Affiliations
- Jilin Municipal Center for Disease Control and Prevention, Jilin City, Jilin Province, China.
- State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
- Tongliao Municipal Center for Disease Control and Prevention, Tongliao City, Inner Mongolia Autonomous Region, China.
- State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases (Zhejiang University), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan City, Hubei Province, China. China Academy of Chinese Medical Sciences, Beijing, China. Shanghai Institute of Infectious Disease and Biosafety, Shanghai, China.
Abstract
What is already known about this topic?
An outbreak of coronavirus disease 2019 (COVID-19) of Omicron BA.2 emerged in Jilin City since March 3, 2022, which involved in 27,036 cases by April 12. The vaccination program with inactivated COVID-19 vaccines has been implemented since the beginning of 2021.
What is added by this report?
The incidences of moderate, severe, and critical cases in the whole population of the group of 0+1 dose were 1.82-, 9.49-, and 3.85-fold higher than those in the group of 2 doses, and 5.03-, 44.47-, and ∞-fold higher than those received 3 doses vaccination. For the population ≥60 years, the incidences of moderate, severe, and critical cases in the group of 0+1 dose were 29.92, 9.62, and 4.27 per 100,000, showing 4.13-, 43.72-, and 4.85-fold higher than 2 doses, as well as 13.28-, 22.37-, and ∞-fold higher than 3 doses.
What are the implications for public health practice?
The incidences of each type of COVID-19 in the population who were fully vaccinated or booster vaccinated in Jilin City were significantly lower than those who were unvaccinated and/or partially vaccinated. Booster vaccination with homologous inactivated vaccines induces stronger protectiveness for COVID-19 caused by variant of concern (VOC) Omicron.
MeSH
Vaccines, Incidence, Vaccination, Covid-19
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