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Journal Article Epublish 77 citations

PubMed: 35997450 DOI: 10.3390/jfb13030112

Unveiling Antimicrobial and Insecticidal Activities of Biosynthesized Selenium Nanoparticles Using Prickly Pear Peel Waste.

J Funct Biomater 13(3)

Authors: Amr H Hashem, Tharwat A Selim, Mohammed H Alruhaili, Samy Selim, Dalal Hussien M Alkhalifah, Soad K Al Jaouni, Salem S Salem

Affiliations

  • Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt.
  • Zoology and Entomology Department, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt.
  • Medical Microbiology and Parasitology Department, Faculty of Medicine, King AbdulAziz University, Jeddah 21589, Saudi Arabia.
  • Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72341, Saudi Arabia.
  • Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
  • Department of Hematology/Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Abstract

In the current study, prickly pear peel waste (PPPW) extract was used for the biosynthesis of selenium nanoparticles through a green and eco-friendly method for the first time. The biosynthesized SeNPs were characterized using UV-Vis, XRD, FTIR, TEM, SEM, EDX, and mapping. Characterization results revealed that biosynthesized SeNPs were spherical, polydisperse, highly crystalline, and had sizes in the range of 10-87.4 nm. Antibacterial, antifungal, and insecticidal activities of biosynthesized SeNPs were evaluated. Results revealed that SeNPs exhibited promising antibacterial against Gram negative ( and ) and Gram positive ( and ) bacteria where MICs were 125, 125, 62.5, and 15.62 µg/mL, respectively. Moreover, SeNPs showed potential antifungal activity toward and where MICs were 3.9 and 7.81 µg/mL, respectively. Furthermore, tested crud extract and SeNPs severely induced larvicidal activity for tested mosquitoes with LC and LC of 219.841, 950.087 mg/L and 75.411, 208.289 mg/L, respectively. The fecundity and hatchability of mosquito were significantly decreased as applied concentrations increased either for the crude or the fabricated SeNPs extracts. In conclusion, the biosynthesized SeNPs using prickly pear peel waste have antibacterial, antifungal, and insecticidal activities, which can be used in biomedical and environmental applications.

MeSH

Bacteria, Nanoparticles

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