System Maintenance Notice

Please note that maintenance work is scheduled between 4 AM and 5 AM - CET. During this time, you may experience reduced performance. Thanks for your patience.

Publications

Journal Article Review Epublish 31 citations

PubMed: 37880734 DOI: 10.1186/s13048-023-01296-x

Potential factors result in diminished ovarian reserve: a comprehensive review.

J Ovarian Res 16(1):208

Authors: Qinying Zhu, Yi Li, Jianhong Ma, Hao Ma, Xiaolei Liang

Affiliations

  • The First Clinical Medical College of Lanzhou University, Lanzhou, China.
  • Department of Obstetrics and Gynecology, Key Laboratory for Gynecologic Oncology Gansu Province, The First Hospital of Lanzhou University, No.1, Donggangxi Rd, Chengguan District, 730000, Lanzhou, China.

Abstract

The ovarian reserve is defined as the quantity of oocytes stored in the ovary or the number of oocytes that can be recruited. Ovarian reserve can be affected by many factors, including hormones, metabolites, initial ovarian reserve, environmental problems, diseases, and medications, among others. With the trend of postponing of pregnancy in modern society, diminished ovarian reserve (DOR) has become one of the most common challenges in current clinical reproductive medicine. Attributed to its unclear mechanism and complex clinical features, it is difficult for physicians to administer targeted treatment. This review focuses on the factors associated with ovarian reserve and discusses the potential influences and pathogenic factors that may explain the possible mechanisms of DOR, which can be improved or built upon by subsequent researchers to verify, replicate, and establish further study findings, as well as for scientists to find new treatments.

MeSH

Therapeutics, Ovary, Oocytes, Ovarian Reserve

Cited by