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Publications

Journal Article Review Research Support, N.I.H., Extramural Ppublish 45 citations

PubMed: 38310921 DOI: 10.1016/S2213-8587(23)00361-3

Air pollution exposure and cardiometabolic risk.

Lancet Diabetes Endocrinol 12(3):196-208

Authors: Sanjay Rajagopalan, Robert D Brook, Pedro R V O Salerno, Brendan Bourges-Sevenier, Philip Landrigan, Mark J Nieuwenhuijsen, Thomas Munzel, Salil V Deo, Sadeer Al-Kindi

Affiliations

  • University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Division of Cardiovascular Diseases, Department of Internal Medicine, Wayne State University, Detroit, MI, USA.
  • University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Program for Global Public Health and the Common Good, Boston College, Boston, MA, USA; Centre Scientifique de Monaco, Monaco.
  • ISGlobal, Centre for Research in Environmental Epidemiology, Barcelona, Spain.
  • Department of Cardiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany; German Center of Cardiovascular Research, Partner-Site Rhine-Main, Germany.
  • Louis Stokes Cleveland VA Medical Center, Case Western Reserve School of Medicine, Cleveland, OH, USA.
  • DeBakey Heart and Vascular Center, Houston Methodist, Houston, TX, USA.

Abstract

The Global Burden of Disease assessment estimates that 20% of global type 2 diabetes cases are related to chronic exposure to particulate matter (PM) with a diameter of 2·5 μm or less (PM 2·5). With 99% of the global population residing in areas where air pollution levels are above current WHO air quality guidelines, and increasing concern in regard to the common drivers of air pollution and climate change, there is a compelling need to understand the connection between air pollution and cardiometabolic disease, and pathways to address this preventable risk factor. This Review provides an up to date summary of the epidemiological evidence and mechanistic underpinnings linking air pollution with cardiometabolic risk. We also outline approaches to improve awareness, and discuss personal-level, community, governmental, and policy interventions to help mitigate the growing global public health risk of air pollution exposure.

MeSH

Diabetes Mellitus, Air Pollution, Air, Environmental Pollution

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