Journal Article Review Epublish 62 citations
PubMed: 38474512 DOI: 10.3390/molecules29051000
Quercetin, a Flavonoid with Great Pharmacological Capacity.
Molecules 29(5)
Authors: Eber Josue Carrillo-Martinez, Flor Yohana Flores-Hernández, Adriana María Salazar-Montes, Hector Fabián Nario-Chaidez, Luis Daniel Hernández-Ortega
Affiliations
- Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara 44270, Mexico.
- Instituto de Investigación en Enfermedades Crónico-Degenerativas, Centro de Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Guadalajara 44340, Mexico.
- Sistemas y Servicios Oncológicos de Latinoamérica S.A. de C.V. Zapopan 45079, Mexico.
- Centro de Investigación Multidisciplinaria en Salud, Centro Universitario de Tonalá, Universidad de Guadalajara, Tonalá 45425, Mexico.
Abstract
Quercetin is a flavonoid with a low molecular weight that belongs to the human diet's phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (ROC), which act as reducing agents by chelating transition-metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, different pharmacological properties of quercetin have been described, such as carcinostatic properties; antiviral, antihypertensive, and anti-inflammatory properties; the ability to protect low-density lipoprotein (LDL) oxidation, and the ability to inhibit angiogenesis; these are developed in this review.
MeSH
Lipoproteins, Ldl, Nanoparticles, Flavonoids, Free Radicals, Quercetin
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