Journal Article Review Epublish
PubMed: 40271071 DOI: 10.3389/fphar.2025.1511011
Role of in neurodegenerative diseases: current evidence and future directions.
Front Pharmacol 16:1511011
Authors: Huaiqing Luo, Siwen Wei, Shujun Fu, Li Han
Affiliations
- Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Health Science Center, Changsha, Hunan, China. Institute of Interdisciplinary Studies, Hunan Normal University Health Science Center, Changsha, Hunan, China.
- Department of Immunology, Jishou University School of Medicine, Jishou, Hunan, China.
- Hunan Provincial Key Laboratory of New Pharmaceutical Preparation, Changsha Medical University, Changsha, Hunan, China.
Abstract
Neurodegenerative diseases are caused by the progressive degeneration of neurons and/or their myelin sheaths, ultimately leading to cognitive and motor dysfunction. Due to their complex pathogenesis and the limited efficacy of therapeutic drugs, these diseases have attracted significant attention. , belongs to family Amaranthaceae, has been extensively used in the traditional and folk medicines for the treatment of various ailments. Modern research has revealed that possesses various pharmacological effects, including cardiocerebrovascular protection, immune regulation, antioxidation, and anti-aging. Furthermore, the neuroprotective effects of have been confirmed by numerous scientific studies. This review focuses on the primary pharmacological effects and mechanisms of in the prevention and treatment of neurodegenerative diseases, as well as their potential application prospects. This review aims to provide insights into the potential clinical applications and research directions of in neurodegenerative diseases.
MeSH
Neuroprotection, Research, Therapeutics, Neurodegenerative Diseases