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Laurent Brochard is an expert in Critical care at St. Michael's Hospital (Canada). As of October 2026, ScienceLeadR ranks Laurent Brochard in the top 1% of experts worldwide for Respiratory Insufficiency, Respiratory Distress Syndrome and Lung Injury. Laurent Brochard has authored 927 publications, the most recent in 2026, and is an investigator in 72 clinical trials, 13 of them ongoing. SLR score: 5,028 (community average: 125). How the SLR is computed.

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Laurent Brochard St. Michael's Hospital Canada
5 028 ScienceLeadR Reputation 5028

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Critical care

Subspecialties: Pulmonology - Public Health

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Organizations

Career arc: 1988 - 2026
Source: PubMed

École des Ponts ParisTech

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 927

Citations

Citations: 97 779 1st author: 46 Last author: 337 Unique author: 52

Main journals

Intensive Care Med 187
Am J Respir Crit Care Med 163
Crit Care 74
Crit Care Med 55
Ann Intensive Care 28

Best Journals

JAMA 23
N Engl J Med 12
Intensive Care Med 7

Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort.
PMID 42714473 — mortality, phenotype, critical care, intensive care units, ventilation, weaning		Intensive Care Med20260
Extracorporeal CO 2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial).
PMID 42693471 — pulmonary disease, chronic obstructive, ventilation		Crit Care20261
ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.
PMID 42611192 — physiology, critical care, intensive care units, ventilation		Intensive Care Med20260
Patient-ventilator Dyssynchrony: Detection, Importance, and Management.
PMID 42486564		Clin Chest Med20262
Publisher Correction: Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome.
PMID 42474727 — lung, critical care, intensive care units, diaphragm, ventilation, respiratory distress syndrome		Intensive Care Med20260

Clinical Studies 72

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 24 Study Chair: 1

By phase:

N/A 65
Phase 3 3
Phase 2/Phase 3 2
Phase 1 1
Phase 1/Phase 2 1

By status:

Completed 38
Recruiting 14
Unknown 9
Terminated 6
Active not recruiting 4
Not yet recruiting 1

By type:

Interventional 41
Observational 31

By Monocentric/Multicentric:

monocentric 45
multicentric2to4 9
multicentric5to9 2
multicentricup10 16

Main Topics

Cohort/Consortium Investigators 9

Ongoing Clinical Trials

13 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
DIAPHRAGM STRENGTH AND LUNG VOLUMES
NCT07206459 — research design, lung, electromyography, tomography, healthy volunteers, air, research, records, intensive care units, diaphragm, ventilation		N/AActive not recruiting2024
PREdicting Failure of Non inVasIve Ventilatory Support Using Non invaSIve mONitoring in Non intubated Patients With Acute Hypoxemic Respiratory Failure or Post extubation Failure The PREVISION Study
NCT06716463 — noninvasive ventilation, tomography, respiratory insufficiency, hypoventilation, diaphragm, ventilation, cannula, weaning		N/ARecruiting2025
Pressure Muscle Index and Threshold of Over assistance During Pressure Support Ventilation
NCT06494085 — mechanics, tidal volume, lung, muscles, acute lung injury, respiratory mechanics, respiration, respiratory insufficiency, intensive care units, ventilation, physical exertion, ventilators, mechanical		N/ARecruiting2024
Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation
NCT06445049 — pilots, respiration, physicians, intensive care units, respiratory rate, ventilation, physical exertion, men		N/ANot yet recruiting2024
Susceptibility for Entrainment Role of Ventilator Settings on the Occurrence of Reverse Triggering and Its Physiological Consequences the SEVeRe Study
NCT06293976 — arterial pressure, tidal volume, muscles, respiration, hypnotics and sedatives, respiration, artificial, air, body weight, diaphragm, respiratory rate, ventilation, physical exertion, respiratory muscles, disease susceptibility		N/ARecruiting2025

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Sources: PubMed, OpenAlex, ClinicalTrials, EU CTIS