Nicola Fazio, MD, PhD is an expert in Oncology at Fondazione IRCCS Istituto Nazionale dei Tumori (Italy). As of October 2026, ScienceLeadR ranks Nicola Fazio in the top 1% of experts worldwide for Carcinoma and Gastrointestinal Neoplasms. Nicola Fazio has authored 484 publications, the most recent in 2026, and is an investigator in 33 clinical trials, 15 of them ongoing. SLR score: 2,242 (community average: 125). How the SLR is computed.

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Oncology

Subspecialties: Endocrinology - Surgery - Hematology

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

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Short Biography

Nicola Fazio graduated at the University of L’Aquila, Italy, Faculty of Medicine and Surgery, in 1988, where he also specialised in Internal Medicine in 1993.

In 2002 he specialized in Medical Oncology at University of Milan.

In 2013 he gained his Ph.D. in Digestive Oncology at the University of Rome “La Sapienza”.

Fazio is currently Director of the Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumours and Director of the Programme in Digestive and Neuroendocrine Tumours at the European Institute of Oncology, in Milan, Italy, where he has been working since 1995.

Since 2015 he is head of the IEO ENETS Centre of Excellence for GEP NENs and lung NETs.

From 2013 to 2019 he served as coordinator of the Italian (AIOM/ITANET) neuroendocrine neoplasms guidelines.

Fazio is full member of American Society of Clinical Oncology (ASCO) since 2000 and full member of the European Society for Medical Oncology (ESMO) since 2002. He has

been serving as ESMO Faculty Coordinator for Neuroendocrine, Endocrine and

CUP for the period 2016-2019 and he is currently member of the NET end endocrine tumors ESMO faculty. He served as chair of the ESMO NEN Preceptorship in 2017, 2018, 2019 and 2021 and chair of the ESMO NEN Advanced Course in 2019 and 2021.

Since 2015 he has been member of the European Neuroendocrine Tumour Society (ENETS) Advisory Board and he served as Advisory Board Speaker for the period 2018-2020. Since 2020 he is member of ENETS executive committee. Between 2021 and 2024 he served as chair of the ENETS certification of centers of excellence and co-chair of the academic database research activity. In 2024 he has been nominated ENETS President Elect; he will take over the active presidency in March 2026.

His research has focused on multidisciplinary and translational clinical research in neuroendocrine neoplasms and gastrointestinal cancers.

He has participated as invited speaker in several national and international meetings and has co-authored more than 300 publications in peer-reviewed journals.


Organizations

Career arc: 1995 - 2026

Source: PubMed

European Institute of Oncology

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 484

Citations

Citations: 14 098 1st author: 48 Last author: 107 Unique author: 5


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Irinotecan Plus Cetuximab Rechallenge Versus Trifluridine/Tipiracil Plus Bevacizumab as Third-Line Treatment in Circulating Tumor DNA-Selected Metastatic Colorectal Cancer (ROMANCE Trial).
PMID 42907240 — circulating tumor dna, cetuximab, trifluridine, neoplasms, bevacizumab, therapeutics, colorectal neoplasms, irinotecan
Clin Colorectal Cancer20260
Circulating tumor DNA tumor fraction as a biomarker in refractory metastatic colorectal cancer: findings from the CAVE-2 GOIM trial.
PMID 42787936 — circulating tumor dna, caves, neoplasms, biomarkers, therapeutics, colorectal neoplasms
J Liq Biopsy20260
Predictive biomarkers for cetuximab-based rechallenge therapy in metastatic colorectal cancer: a pooled analysis of the CAVE and CAVE-2 GOIM studies.
PMID 42661856 — cetuximab, progression-free survival, caves, neoplasms, liver, biomarkers, neoplasm metastasis, therapeutics, colorectal neoplasms, liquid biopsy
ESMO Gastrointest Oncol20260
Rate and risk factors of venous thromboembolism during neoadjuvant chemotherapy for advanced ovarian cancer: a retrospective analysis from a referral center.
PMID 42546374 — thromboembolism, ovary, neoplasms, drug therapy, ovarian neoplasms, risk factors, venous thromboembolism, chemotherapy
Int J Gynecol Cancer20260
Circulating tumor DNA to predict the risk of venous thromboembolism in locally advanced rectal cancer.
PMID 42468056 — thromboembolism, circulating tumor dna, incidence, neoplasms, rectal neoplasms, venous thromboembolism, dna, prospective studies
Cancer Treat Res Commun20260

Clinical Studies 33

Sources: ClinicalTrials, EU CTIS

Synthesis

Principal Investigator: 5 Study Chair: 2

By phase:

Phase 2 14
Phase 3 11
N/A 8

By status:

Recruiting 13
Completed 11
Active not recruiting 4
Not yet recruiting 2
Unknown 2
Terminated 1

By type:

Interventional 26
Observational 7

By Monocentric/Multicentric:

monocentric 7
multicentric2to4 2
multicentric5to9 2
multicentricup10 22

Main Topics

Ongoing Clinical Trials

15 ongoing trials started since 2021, where this expert is an investigator

Source: ClinicalTrials

Study Phase Status Start
Phase 3 study of RMC 6236 in patients with previously treated metastatic PDAC
2024-516063-89-00 — adenocarcinoma, therapeutics
Phase 3Active not recruiting2025
A study in people with advanced extrapulmonary neuroendocrine cancer to compare obrixtamig plus carboplatin and etoposide treatment with standard chemotherapy
2025-523869-22-00 — neoplasms, multiple chronic conditions, drug therapy, therapeutics, etoposide, carboplatin, carcinoma, neuroendocrine, chemotherapy, carcinoma
Phase 3Recruiting2026
A trial to learn how well sonesitatug vedotin and capecitabine with or without rilvegostomig work and how safe they are in adults with cancers of the stomach and esophagus
2024-519787-40-00 — stomach, esophagus, esophagogastric junction, neoplasms, adenocarcinoma, work, therapeutics, esophageal neoplasms, capecitabine, stomach neoplasms
Phase 3Not yet recruiting2026
177Lu edotreotide compared to everolimus in neuroendocrine tumors of the lung and thymus
2022-502154-13-00 — lung, somatostatin, safety, neoplasms, everolimus, neuroendocrine tumors, receptors, somatostatin, patient reported outcome measures, thymus gland, therapeutics, receptors, peptide
Phase 3Recruiting2023
Phase II open label single arm study of PembrolizumAb combiNeD with cisplatin or carbOplatin and etoposide in treatment na ve advanced meRkel cell cArcinoma (MCC) (PANDORA Trial)
2022-500988-12-00 — cells, merkel cells, therapeutics, genes, mcc, etoposide, carboplatin, carcinoma, merkel cell, carcinoma
Phase 2Recruiting2023

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