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Publications

Journal Article Review Epublish 15 citations

PubMed: 39219747 DOI: 10.2147/CLEP.S459600

Epidemiology of Invasive Candidiasis.

Clin Epidemiol 16:549-566

Authors: Derek J Bays, Emily N Jenkins, Meghan Lyman, Tom Chiller, Nora Strong, Luis Ostrosky-Zeichner, Martin Hoenigl, Peter G Pappas, George R Thompson Iii

Affiliations

  • Department of Internal Medicine, Division of Infectious Diseases, School of Medicine, University of California Davis, Sacramento, CA, USA.
  • ASRT, Inc, Atlanta, GA, USA.
  • Mycotic Disease Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Division of Infectious Diseases, Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
  • Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Clinical and Translational Fungal Working Group, University of California San Diego, La Jolla, CA, USA.
  • Division of Infectious Diseases, Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Department of Medical Microbiology and Immunology, University of California-Davis, Davis, CA, USA.

Abstract

Invasive candidiasis (IC) is an increasingly prevalent, costly, and potentially fatal infection brought on by the opportunistic yeast, . Previously, IC has predominantly been caused by which is often drug susceptible. There has been a global trend towards decreasing rates of infection secondary to and a rise in non- species with a corresponding increase in drug resistance creating treatment challenges. With advances in management of malignancies, there has also been an increase in the population at risk from IC along with a corresponding increase in incidence of breakthrough IC infections. Additionally, the emergence of creates many challenges in management and prevention due to drug resistance and the organism's ability to transmit rapidly in the healthcare setting. While the development of novel antifungals is encouraging for future management, understanding the changing epidemiology of IC is a vital step in future management and prevention.

MeSH

Epidemiology, Candidiasis, Pharmaceutical Preparations, Candidiasis, Invasive, Infections, Drug Resistance

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