Frank Porreca is an expert in Biochemistry at Mayo Clinic (United States, Scottsdale) (United States). As of September 2026, ScienceLeadR ranks Frank Porreca in the top 1% of experts worldwide for Pain and Headache. Frank Porreca has authored 695 publications, the most recent in 2026, and is an investigator in 4 clinical trials. SLR score: 3,269 (community average: 125). How the SLR is computed.

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Frank Porreca Mayo Clinic (United States, Scottsdale) United States
3 269 ScienceLeadR Reputation 3269
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Biochemistry

Subspecialties: Neurology

Full career – Last 3 years

Main Topics

Publications and Clinical Studies

Publications – Clinical Studies

Profile data updated on

Expert Rankings

Top experts on the MeSH terms this expert works on

Organizations

Career arc: 1987 - 2026

Source: PubMed

University of Arizona

Publications Synthesis

Sources: PubMed, OpenAlex

Number : 695

Citations

Citations: 42 554 1st author: 50 Last author: 317 Unique author: 2


Breakdown by type

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Latest Publications

5 most recent indexed articles

Source: Pubmed

Title Journal Year Citations
Clinical and preclinical investigation of the mechanism promoting aura in post-traumatic headache and inhibition of pain-related behavior in mice by onabotulinumtoxinA.
PMID 42775980 — headache, pain, migraine disorders, post-traumatic headache, optogenetics
Pain20260
Identification of a central CGRP circuit for trigeminal V1-mediated migraine-like pain in mice.
PMID 42339700 — headache, cells, genes, pituitary adenylate cyclase-activating polypeptide, central amygdaloid nucleus, neurons, pain, acute pain, migraine disorders, parabrachial nucleus, photophobia, trigeminal nerve, neurology
Brain20261
Sexually dimorphic mediation of experimental post-traumatic headache by orexin receptor signaling.
PMID 42302125 — headache, pain, sleep, stress, physiological, migraine disorders, orexin receptors, post-traumatic headache, negotiating, orexins
Pain20260
Dual Roles of Voltage-gated Calcium Channels and γ-Aminobutyric Acid-mediated Signaling in Modulating Neurotensin Receptor Type 2-induced Antinociception.
PMID 42262386 — clustered regularly interspaced short palindromic repeats, chronic pain, anesthesiology, neurons, pain, receptors, neurotensin, analgesia, calcium channels, calcium, therapeutics, neurotensin, spine
Anesthesiology20260
Sex-dependent central amygdala physiology after supradural CGRP exposure is associated with migraine-like behaviors.
PMID 42251283 — headache, cells, calcitonin gene-related peptide receptor antagonists, physiology, central amygdaloid nucleus, hypersensitivity, migraine disorders, amygdala, sex
J Headache Pain20260

Clinical Studies 4

Sources: ClinicalTrials, EU CTIS

Synthesis

By phase:

N/A 3
Phase 3 1

By status:

Completed 3
Active not recruiting 1

By type:

Interventional 4

By Monocentric/Multicentric:

monocentric 2
multicentric2to4 0
multicentric5to9 0
multicentricup10 2

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